Instead of a determinant, we can use the cyclic unit-vector cross product rules directly: $\hat x\times\hat y=\hat z$, $\hat y\times\hat z=\hat x$, $\hat z\times\hat x=\hat y$, and reversing the order of any pair flips the sign, so $\hat x\times\hat z=-\hat y$.
Apply this to $\vec v\times\vec B$:
\[ \vec v\times\vec B=(5\hat x)\times(-6\hat z)=-30(\hat x\times\hat z)=-30(-\hat y)=30\hat y \]Add the electric field term to get the total force per unit charge:
\[ \vec E+\vec v\times\vec B=4\hat y+30\hat y=34\hat y \]So the total force is $\vec F=34q\hat y$.
Comparing directions: the result $34q\hat y$ has a component only along $\hat y$, exactly the direction of $\vec E=4\hat y$, and $\hat y$ is orthogonal to $\hat z$, the direction of $\vec B$. So the force is along $\vec E$ and perpendicular to $\vec B$.
\[ \boxed{\text{Force is along}\ \vec E,\ \text{perpendicular to}\ \vec B} \]