Question:medium
A hypertensive patient wants to conceive. Which of the following medicines needs to be stopped?
A hypertensive patient wants to conceive. Which of the following medicines needs to be stopped?
Show Hint
One class of antihypertensives causes fetal renal damage and is contraindicated in all trimesters of pregnancy.
Updated On: Jun 23, 2026
- Calcium Channel Blockers
- ACE inhibitors
- Alpha Methyl dopa
- Labetolol
Show Solution
The Correct Option is B
Solution and Explanation
Safety of antihypertensives in pregnancy: Methyldopa is the drug of choice; labetalol and nifedipine (CCB) are safe alternatives. ACE inhibitors are absolutely contraindicated in pregnancy. They cross the placenta and cause fetal renal tubular dysplasia, oligohydramnios, limb contractures, pulmonary hypoplasia, and neonatal renal failure (ACE inhibitor fetopathy). Angiotensin II receptor blockers (ARBs) carry the same risk. When a hypertensive woman plans pregnancy, ACE inhibitors must be switched to a safer agent before conception. \[\boxed{\text{ACE inhibitors (Option B)}}\]
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