A 70 kg calf was given a drug X at a dose of 100 mg/kg body weight. The half-life of the drug X is 10 hours and its initial plasma concentration is 1.9 mg/ml. True statement about drug X is/are
(A). Clearance is around 0.02 litre/hour
(B). Volume of distribution is around 3.68 L
(C). Elimination rate constant is 0.0693
(D). Clearance is around 0.2 litre/hour
Choose the correct answer from the options given below:
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Always convert units into standard forms first (e.g., converting initial concentration from $1.9 \text{ mg/ml}$ to $1900 \text{ mg/L}$ to match the total dose in mg).
This prevents calculation errors by a factor of 1000.