Question:medium

A 35-year-old male presents with recurrent headaches. On further investigation, MRI is obtained. What is the most likely diagnosis?

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Dural-based intracranial mass with headache = think of meningioma.
Updated On: May 14, 2026
  • Meningioma
  • Glioma
  • Medulloblastoma
  • Pilocytic astrocytoma
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The Correct Option is A

Solution and Explanation

Step 1: Understanding the Question:
The MRI (as implied by the common clinical scenario) shows a dural-based, well-circumscribed, intensely enhancing extra-axial mass.
Step 2: Detailed Explanation:

Meningioma Characteristics: These are the most common benign intracranial tumors. They arise from the arachnoid cap cells of the meninges. On MRI, they are typically "extra-axial," meaning they are outside the brain parenchyma and compress the brain rather than invading it.

Imaging Features: 1. Intense enhancement: They show uniform, bright enhancement after contrast. 2. Dural Tail Sign: This is a pathognomonic sign where the thickened dura mater adjacent to the tumor enhances, resembling a tail.

Differentials - Glioma: These are "intra-axial" tumors (inside the brain tissue). They often have ill-defined borders and show varying degrees of necrosis and edema.

Differentials - Pediatric Tumors: Medulloblastoma and Pilocytic Astrocytoma are primarily pediatric tumors and are usually located in the posterior fossa (cerebellum), not in the cerebral convexities of a 35-year-old.

Pathology: Meningiomas may show "psammoma bodies" (laminated calcifications) and "whorled" patterns of spindle cells.

Step 3: Final Answer:
The dural-based location and characteristic enhancement pattern seen on MRI are diagnostic of a Meningioma.
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