Question:easy
A 26 years old male with backache, morning stiffness, chest expansion and reddening of eyes with an X-ray presented in OPD. Most likely diagnosis for this patient is
[X-ray shows bamboo spine appearance with sacroiliac joint involvement]
A 26 years old male with backache, morning stiffness, chest expansion and reddening of eyes with an X-ray presented in OPD. Most likely diagnosis for this patient is
[X-ray shows bamboo spine appearance with sacroiliac joint involvement]
[X-ray shows bamboo spine appearance with sacroiliac joint involvement]
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Bamboo spine on X-ray with morning stiffness and uveitis in a young male is pathognomonic of a seronegative spondyloarthropathy.
Updated On: Jun 23, 2026
- Rheumatoid arthritis
- Ankylosing spondylitis
- Paget's disease
- Osteopetrosis
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The Correct Option is B
Solution and Explanation
Pattern recognition approach:
Key clinical clues in this case:
1. Young male (26 years)
2. Inflammatory back pain + morning stiffness (improves with activity)
3. Reduced chest expansion (costovertebral joint involvement)
4. Reddening of eyes = anterior uveitis (most common extra-articular feature of AS)
5. X-ray = bamboo spine (syndesmophytes bridging vertebral bodies)
This is the classic presentation of Ankylosing Spondylitis, a seronegative HLA-B27 associated spondyloarthropathy.
The 5 inflammatory back pain criteria (ASAS):
- Age of onset $<$ 40 years
- Insidious onset
- Improvement with exercise
- No improvement with rest
- Pain at night, improving on arising
Rheumatoid arthritis $\rightarrow$ symmetric peripheral arthritis, predominantly females, RF positive. Paget's disease $\rightarrow$ elderly, bone deformity, elevated ALP. Osteopetrosis $\rightarrow$ congenital, marble bone disease.
\[\boxed{\text{Ankylosing spondylitis}}\]
Key clinical clues in this case:
1. Young male (26 years)
2. Inflammatory back pain + morning stiffness (improves with activity)
3. Reduced chest expansion (costovertebral joint involvement)
4. Reddening of eyes = anterior uveitis (most common extra-articular feature of AS)
5. X-ray = bamboo spine (syndesmophytes bridging vertebral bodies)
This is the classic presentation of Ankylosing Spondylitis, a seronegative HLA-B27 associated spondyloarthropathy.
The 5 inflammatory back pain criteria (ASAS):
- Age of onset $<$ 40 years
- Insidious onset
- Improvement with exercise
- No improvement with rest
- Pain at night, improving on arising
Rheumatoid arthritis $\rightarrow$ symmetric peripheral arthritis, predominantly females, RF positive. Paget's disease $\rightarrow$ elderly, bone deformity, elevated ALP. Osteopetrosis $\rightarrow$ congenital, marble bone disease.
\[\boxed{\text{Ankylosing spondylitis}}\]
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