Question:medium
A 20-year-old man presents with swelling of the wrist for the last two years. Histopathological examination shows spindle-shaped cells and Verocay bodies. What is the diagnosis?
A 20-year-old man presents with swelling of the wrist for the last two years. Histopathological examination shows spindle-shaped cells and Verocay bodies. What is the diagnosis?
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Palisading nuclei forming a named body point to one nerve sheath tumour.
Updated On: Jun 23, 2026
- Lipoma
- Dermoid cyst
- Neurofibroma
- Schwannoma
Show Solution
The Correct Option is D
Solution and Explanation
Anchor on the buzzword: Verocay bodies equal schwannoma. Lipoma is made of mature adipocytes, and a dermoid cyst is lined by skin with adnexal structures, so neither shows spindle cells with palisading nuclei. The real trap is neurofibroma, the other peripheral nerve sheath tumour, but it has axons coursing through the lesion and does NOT form Verocay bodies. A schwannoma is encapsulated, pushes nerve fibres to its periphery, and shows two textures, the dense Antoni A and loose Antoni B, with the diagnostic palisaded Verocay bodies in the Antoni A zones, plus diffuse S-100 positivity. The diagnosis is schwannoma.
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